urine test tube

Cellular Energy, Oxidative Damage, Oxalate and Mitochondrial Markers

€ 80,00

Evaluates mitochondrial function, oxidative stress, and oxalate metabolism through urine analysis.

Your test at a glance

Sample
Urine
Results from receipt
Usually 3–10 days
Fasting
An overnight fast is usually not needed. Follow the kit’s food, drink and collection-timing instructions.

Timing starts when suitable samples arrive at the laboratory. Shipping time is additional. Combined panels may take longer.

WHL will send the full test instructions with your kit or appointment confirmation. Follow these before collecting.

Preparation and important notes

One charge per request. Processing and handling is charged once for the complete request, not for each test or panel. Collection and delivery charges are shown separately at checkout.

- +
SKU: COOM-P Categories: Tags:

Description

The Cellular Energy, Oxidative Damage, Oxalate & Mitochondrial Markers panel from World Health Laboratories is a highly specialized urine-based test designed to assess mitochondrial function, energy metabolism, oxidative stress, and oxalate burden. This advanced analysis offers critical insights into the biochemical processes that power the body’s energy production systems and reveal hidden dysfunctions at the cellular level.

What It Tests

This panel measures a wide range of organic acids that are involved in the Krebs cycle (citric acid cycle), glycolysis, and fatty acid metabolism. It also identifies markers for oxidative stress, genetic or acquired mitochondrial dysfunction, and oxalate overproduction or accumulation, which can have downstream effects on energy, cognition, pain, and chronic disease.

Key Metabolites Include:

  • Lactic acid & Pyruvic acid – Indicators of impaired aerobic metabolism or low oxygen states
  • Succinic, Fumaric, Malic, Isocitric, α-Ketoglutaric acids – Mitochondrial intermediates, often elevated with nutrient deficiencies (B-vitamins, CoQ10) or toxin exposure
  • Oxalic, Glycolic, Glyceric acids – Associated with genetic or microbial causes of oxalate toxicity
  • 3-Hydroxy-3-methylglutaric (HMG) – Reflects need for CoQ10 and mitochondrial biosynthesis status
Clinical Relevance

This test is essential for individuals presenting with:

  • Chronic fatigue and low energy
  • Neurodegenerative and neurocognitive symptoms
  • Mood disorders and anxiety
  • Fibromyalgia and unexplained pain syndromes
  • Cardiometabolic dysfunctions (e.g. insulin resistance, obesity)
  • Multiple chemical sensitivities or heavy metal exposure

It helps in identifying:

  • Functional nutrient insufficiencies (B-vitamins, CoQ10, glutathione)
  • Mitochondrial stress due to toxic exposures (e.g. lead, mercury, arsenic)
  • Enzyme blockages in the Krebs cycle and oxidative phosphorylation
  • Imbalances in oxalate metabolism linked to chronic inflammation and joint pain
Clinical Utility

This panel enables:

  • Early detection of mitochondrial inefficiencies before overt symptoms appear
  • Targeted therapeutic strategies: antioxidant support, nutrient repletion, detoxification support
  • Monitoring response to nutritional interventions or environmental exposure mitigation

Sample Type

  • Urine (First Morning Void Preferred) – Non-invasive and ideal for measuring dynamic metabolic byproducts
  • Includes: Evaluation of mitochondrial markers, oxidative damage indicators, and oxalate levels
  • Sample requirement: 20 ml midstream urine

Suitable for postal submission.

Additional information

Weight 0,5 kg
Sample Type

Preparing for this test

WHL will send detailed collection, storage and return instructions with your test kit or appointment confirmation. Those test-specific instructions take priority.

Sample: Urine

Fasting: An overnight fast is usually not needed. Follow the kit’s food, drink and collection-timing instructions.

The collection time, container and storage depend on the test. Follow your WHL kit; do not switch between a spot sample and a 24-hour collection.

Do not stop prescribed medicines or prescribed supplements without advice from your treating clinician. Tell WHL about high-dose biotin; some tests need a longer pause. A short supplement pause does not remove all effects of long-term use.

If another test in the same order requires fasting, follow the combined instructions. Ask your clinician or WHL before fasting if you have diabetes, use glucose-lowering medicine, are pregnant, or are arranging testing for a child.

When to expect your results

Usually 3–10 days. This estimate starts when suitable samples reach the laboratory, not on the order or collection date. Shipping is additional. WHL will confirm any test-specific exception; a combined panel follows its slowest component.

Read WHL’s general preparation and reporting guidance

Practical preparation tips

If fasting is requested, drink only plain water in your usual amounts. Do not have coffee, tea, juice, milk, energy drinks, sweets or chewing gum. Avoid smoking or vaping that morning. Book an early appointment and eat after collection.

For a planned blood test, avoid alcohol and unusually strenuous exercise for 24 hours, where practical, and sit quietly for about 15 minutes before collection. Tell WHL if you could not follow the preparation instructions.

Do not extend fasting or change prescribed medication on your own. Ask your clinician first if you have diabetes, need medicine with food, are pregnant, or are arranging testing for a child. WHL’s full test-specific instructions take priority.

Sources for this general preparation guidance

Other laboratories’ methods and preparation rules can differ. These sources support the general advice; WHL confirms the instructions for the method used for your test.

Related products