Vitamins and Methylation Cofactors Markers

Beschrijving

Unlock Functional Clarity with Biochemical Precision

This advanced urine-based panel offers a functional and clinically validated assessment of vitamin sufficiency and methylation cofactor needs by analyzing a broad array of organic acid biomarkers. Rather than relying solely on serum levels, which may not reflect intracellular activity, this test evaluates metabolic intermediates that reflect how vitamins are being used at the cellular level—offering a true picture of physiological need.

What This Panel Measures

The panel assesses a wide spectrum of vitamin-related and methylation-related metabolites, including:

• Functional B-vitamin markers (B1, B2, B3, B5, B6, B7, B9, B12)
• Organic acids indicating vitamin need such as methylmalonic acid, glutaric acid, and xanthurenic acid
• Indicators of mitochondrial function and energy metabolism like succinic, malic, and α-ketoglutaric acid
• Markers related to methylation including FIGLU, uracil, thymine, and kynurenic acid

Clinical Applications

This panel is ideal for individuals or patients with:

• Fatigue, depression, poor stress tolerance
• Suspected vitamin deficiencies or poor nutrient absorption
• Autism spectrum disorders and neurological symptoms
• High oxidative stress or inflammation
• Mitochondrial dysfunction or metabolic disorders
• Use of oral contraceptives or other medications affecting B-vitamin status

By identifying specific biochemical imbalances, clinicians can personalize supplementation strategies with precision and confidence.

Key Biomarkers and Their Significance

This table highlights key functional indicators, but the full panel also measures a broader range of clinically significant metabolites, including Uracil, Thymine, Ethylmalonic Acid, 3-Hydroxy-3-methylglutaric Acid, N-Acetylcysteine Acid, Methylcitric Acid, Pantothenic Acid, Picolinic Acid, Pimelic Acids, 3-Methylglutaric Acid, 3-Methylglutaconic Acid, β-Hydroxyisovaleric Acid, α-Ketoisovaleric Acid, α-Ketoisocapric Acid, α-Keto-β-methylvaleric Acid, Succinic Acid, Malic Acid, α-Ketoglutaric Acid, and Ascorbic Acid.
These additional markers provide further insight into mitochondrial performance, detoxification needs, oxidative stress, and nutrient utilization, making this panel one of the most comprehensive tools available for functional assessment.

Why Use This Panel?

Conventional nutrient tests often miss subtle intracellular imbalances. This panel bridges that gap by:

• Detecting functional nutrient needs before clinical deficiency develops
• Supporting methylation pathway assessments, vital for neurological, cardiovascular, and detoxification health
• Aiding in the interpretation of symptoms that are otherwise non-specific or multifactorial

Sample Type & Preparation

• Specimen: First morning urine (non-preserved)
• Shipping: Cold pack recommended. Full instructions provided upon ordering.
• Turnaround Time: Typically 2-7 business days from sample receipt

Ready to Order?

Explore how this panel can uncover hidden nutrient imbalances and support personalized, precision-based interventions.

➡️ Order Now or contact us directly for consultation options.

• Includes: Assessment of various vitamins and methylation cofactors
• Sample requirement: First-morning urine sample

Suitable for postal submission.