LTT – Metal Profile I + II (Comprehensive)

Beschrijving

Includes

All metals from Profiles I and II

Beryllium, cadmium, gold, indium, nickel, palladium, inorganic mercury, lead, tin, zirconium, Aluminium, chromium, cobalt, ethyl-mercury, copper, methyl-mercury, molybdenum, phenyl-mercury, platinum, silver

Lymphocyte Transformation Test (LTT)

The Lymphocyte Transformation Test (LTT) evaluates cell-mediated (Type IV) hypersensitivity reactions by measuring lymphocyte proliferation after exposure to specific substances in vitro.

Unlike IgE allergy tests, LTT detects delayed immune reactions, which are often involved in:

• chronic inflammation
• unexplained fatigue
• neurological symptoms
• implant intolerance
• dental material intolerance
• multi-chemical sensitivity

This makes LTT particularly useful in environmental medicine, dentistry, and implant compatibility assessment.

Clinical purpose

Provides a full metal hypersensitivity overview.

Who should use this

• patients with unexplained chronic symptoms
• implant candidates
• multiple dental restorations
• suspected heavy metal sensitivity

Why this matters

Some metals can induce:

• immune activation
• mitochondrial stress
• endocrine disruption
• neurological complaints

Typical exposure sources

• implants
• industrial alloys
• cosmetics
• vaccines (ethyl-mercury)
• occupational settings

Interpretation Notes

LTT results indicate:

• degree of lymphocyte activation
• potential delayed hypersensitivity
• immune system recognition of substances

Results should be interpreted alongside:

• clinical history
• symptom patterns
• exposure history
• other immune markers

Why WHL LTT testing is valuable

• Supports complex chronic cases
• Adds objective immune data
• Guides implant and dental material selection
• Helps explain unexplained inflammatory symptoms
• Complements toxicology and mineral panels

Read more……..

• Sample requirement: Whole blood