Total:€ 249,00
Amino Acids (Plasma)
€ 160,00
Comprehensive Metabolic Profile for Optimal Health
Beschrijving
World Health Laboratories offers a comprehensive plasma amino acids panel to assess metabolic health, nutrient deficiencies, neurotransmitter precursors, urea cycle function, and detox pathways. Suitable for preventive health, functional medicine, and complex metabolic cases.
1. Purpose & Clinical Significance
- Comprehensive metabolic profiling: Measures concentrations of essential, conditionally essential, and non‑essential amino acids in plasma to screen for metabolic disorders and assess general metabolic health.
- Detects inborn errors of metabolism: Crucial for identifying disorders like phenylketonuria, tyrosinemia, urea cycle defects, and organic acidemias, which can manifest early in life and cause neuro‑developmental complications if untreated mayocliniclabs.com.
- Monitors treatment & dietary interventions: Used in clinical follow-up of dietary therapy effectiveness, especially in metabolic conditions and nutrient insufficiencies.
- Assesses organ function & nutrition: Indicates liver, kidney, endocrine, muscle, and gastrointestinal disorders, as well as nutritional deficiencies and stress responses.
2. Methodology
- Typically analyzed via liquid chromatography–tandem mass spectrometry (LC‑MS/MS), offering precise and sensitive detection for over 40 amino acids.
- For accurate fasting levels, plasma is preferred over urine since it’s less influenced by recent dietary intake.
3. Who Should Test?
- Newborns & infants: For early metabolic screening.
- Patients with unexplained symptoms: Such as developmental delays, fatigue, GI issues, or neuropsychiatric signs.
- Individuals with chronic or organ-related conditions: Including liver/kidney disease, endocrine disorders, muscle wasting, cancer, and malnutrition.
- Athletes, wellness seekers, and those undergoing nutritional therapy: To optimize metabolic and performance outcomes.
Key Amino Acids Monitored & Their Clinical Relevance
| Amino Acid | Category | Clinical Importance |
|---|---|---|
| Phenylalanine | Essential | Diagnoses PKU; elevated levels lead to neurotoxicity if untreated |
| Tyrosine | Non-essential (conditionally essential) | Monitors tyrosinemia; essential in neurotransmitter synthesis |
| Leucine, Isoleucine, Valine (BCAAs) | Essential | Indicates Maple Syrup Urine Disease; involved in muscle metabolism, immune response, insulin regulation |
| Methionine | Essential | Signals homocystinuria; important for methylation and detox processes |
| Homocysteine | Non‑standard but often included | Reflects B‑vitamin status; elevated in cardiovascular and renal disease |
| Citrulline & Ornithine | Non-essential | Key markers for urea cycle disorders |
| Glutamine, Glycine, Alanine, Serine | Non-essential | Provide insight into hepatic, renal, and muscle metabolic health |
| GABA (gamma-aminobutyric acid) | Metabolic/neuro | Related to neurotransmitter balance, mental health regulation |
| Taurine | Conditionally essential | Indicative of oxidative stress, liver/renal impairment |
Why This Test Matters
- Early detection of treatable metabolic disorders can prevent serious long-term outcomes.
- Guides dietary and nutrient therapy based on precise amino acid imbalances.
- Monitors health improvements or deterioration over time through follow‑up measurements.
- Provides a metabolic snapshot, integrating information on organ function, nutrient absorption, stress, and neurotransmitter dynamics.
Summary
The Plasma Amino Acids Test by World Health Laboratories is a robust tool for metabolic health assessment—spanning newborn screening, chronic disease monitoring, and nutritional optimization. Its capacity to measure a wide range of amino acids enhances diagnostic precision, treatment decision-making, and patient monitoring.
- Includes: Analysis of more than 46 amino acids
- Sample requirement: Blood collection
Suitable for postal submission.
Additional information
| Weight | 0,5 kg |
|---|---|
| Dimensions | 25 × 16 × 2,5 cm |
| Sample Type |
