DMPS Test Explained: A Powerful Method for Heavy Metal Detoxification
The DMPS test is a diagnostic tool used to measure the total heavy metal burden in the body, particularly mercury. DMPS (sodium salt of 2,3 Di-Mercapto-1-Propane-Sulphonic acid) is a chelating agent that binds to heavy metals like mercury and lead, as well as essential minerals such as zinc, copper, and iron. It facilitates the excretion of these substances from body depots, making it an effective method for assessing and detoxifying heavy metal accumulation.
How Does the DMPS Test Work?
Once ingested, DMPS is absorbed into the bloodstream, reaching peak concentration within 30 to 50 minutes. The excretion of bound heavy metals and minerals via urine peaks after 2 to 3 hours. This process forms a stable, water-soluble complex, which is eliminated through the urinary system.
The DMPS test utilizes these properties to assess mercury load in the body. The test consists of two urine samples:
- A morning urine sample (before DMPS intake) to establish a baseline.
- A second sample taken 2-3 hours after DMPS ingestion to measure the excretion of mercury from body depots.
By comparing these samples, the test provides a clearer picture of mercury accumulation in the body. To ensure accurate results, the DMPS capsule should be taken on an empty stomach, as it has a stronger affinity for minerals like zinc and copper than mercury. If DMPS binds dietary minerals instead, the test results may underestimate mercury levels.
When is a DMPS Test Recommended?
A DMPS test may be beneficial if there is suspicion of heavy metal toxicity, particularly mercury exposure. Symptoms and conditions potentially linked to mercury accumulation include:
- Anemia
- Anorexia
- High blood pressure
- Depression
- Memory problems
- Irritability and mood swings
- Headaches
- Skin issues
- Gastrointestinal disturbances (diarrhea, bloating)
- Insomnia
- Inflamed gums
- Chronic fatigue
- Fertility issues
- Reduced immune function
Complementary Tests for a Comprehensive Assessment
In addition to the DMPS test, further diagnostic tests can provide a broader understanding of mercury toxicity and its effects on the body:
- Trace Elements in Blood: Individual sensitivity to mercury varies. Assessing nutrient levels, particularly selenium (which plays a role in mercury detoxification), helps determine susceptibility to mercury toxicity.
- Mercury in Saliva Test: The DMPS test measures overall mercury burden, but if mercury exposure from dental amalgam fillings is a concern, a saliva test can specifically evaluate mercury levels from fillings.
- MELISA Test: This test checks for immunological hypersensitivity to metals, including mercury, used in dental and medical practices. Some individuals may experience symptoms at non-toxic exposure levels due to immune reactions.
Conclusion
The DMPS test is a valuable tool for identifying heavy metal toxicity, particularly mercury accumulation. By measuring mercury excretion before and after DMPS administration, this test provides crucial insights into the body’s heavy metal burden. If symptoms of mercury toxicity are present, consulting a healthcare professional and considering additional complementary tests can aid in a comprehensive diagnosis and detoxification plan.
Taking a proactive approach to heavy metal detoxification can improve overall health, energy levels, and well-being. If you suspect mercury toxicity, consider the DMPS test as a first step towards understanding and addressing potential heavy metal exposure.
Literature
- Cerian et al. Estimation of mercury burden in rats by chelation with dimercaptoprocane sulphate; J. Pharmacol. Exo. Ther. 1988:245, 479-84.
- M. Godfrey et al. Confirmation of Mercury retention and toxicity using 2,3-dimercapto-1-propane-sulphonic acid sodium salt (DMPS); J. Adv. Med. Vol 7 (no 1), spring 1994: 19-30
- M.R. Werbach. Nutritional Infuences on Illness. A sourcebook of clinical research. Second edition, Third Line Press, Tarzana, California.,1993.
